About This DocumentΒΆ

SilcsBio offers a suite of computer-aided drug design software including:

  • the patented SILCS functional group mapping approach with capabilities for

    1. small-molecule database screening, fragment-based drug design, and lead optimization, and

    2. excipient screening for biomacromolecular therapeutics;

  • the SSFEP method that delivers free energy calculations 1,000 times faster than standard FEP; and

  • the CGenFF force field parameter assignment engine.

This documentation covers how to install and use the software.